Find A PhysicianHome  |  Library  |  myDownstate  |  Newsroom  |  A-Z Guide  |  E-mail  |  Contact Us  |  Directions
curve gif

OFFICE OF SCIENTIFIC AFFAIRS AND BIOTECHNOLOGY

 

Core Research Laboratory / Facility Descriptions

Cryostat

The Department of Anatomy and Cell Biology maintains a Jung CM 3000 Cryostat Microtome. The instrument is designed for rapid freezing and sectioning of tissue samples. The operating temperature range is from 0°C to -40°C and it can be manually or motor operated. It can be set to section at thickness ranging from 0.5 to 60 µm. Individual investigators have to provide their own slides , and have to do their own sectioning. Staff will provide instruction in the proper usage of the machine. Please call for consultation and estimate of cost.

CONTACT
Dr. Gladys Teitelman
Department of Anatomy and Cell Biology
Basic Science Building, Room 2-94
(718) 270-2950 - Fax (718) 270-3732

Yelena Guz
Basic Science Building, Room 2-94
(718) 270-1472
Box 5
gteitelman@downstate.edu
yguz@downstate.edu


DNA Core Laboratory

SERVICE: The Core Lab runs an enzyme freezer program featuring products from New England BioLabs and Boehringer Mannheim Biochemical, with a 15% discount from the former and a 20% discount off list prices from the latter. Any product that is not maintained in the stock room will be delivered the next day if orders are placed by 3:00p.m.

CONDITIONS OF SALE: All orders, without exception, MUST be accompanied by a signed Purchase Requisition.

CONTACT
Dr. C. Hellen or Mr. R. Romain
Morse Institute for Molecular Genetics - Department of Microbiology and Immunolog
Basic Science Building, Room 3-98
(718) 270-10134, 1248 - Fax (718) 270-2656
Box 44
christopher.hellen@downstate.edu


Foto/Analyst II System

OBJECTIVE: To provide facilities for computer-based gel documentation and image analysis.

SERVICES: The Foto/analyst II workstation acquires images of ethidium bromide-stained agrose gels using an integrating camera configured with a zoom lens, and provides live video and continuous-tone hardcopy output. Thermal prints are of continuous-tone 256 greyscale quality. Video images are digitized and can be saved directly to a computer. The system interfaces directly to a Macintosh Quadra 650 computer, and specialty software allows images to be analyzed for other purposes, such as PCR quantitation.

CONTACT
Dr. C. Hellen or Rodney Romain
Morse Institute for Molecular Genetics - Department of Microbiology and Immunology
Basic Science Building, Room 3-98
(718) 270-1034 - Fax (718) 270-2656
Box 44
christopher.hellen@downstate.edu


Microinjection and Micromanipulation Facility

 

 


Nitric Oxide Measurement Facility

This facility offers determination of nitric oxide (NO) and its reaction products, NO2 and NO3, in liquids such as biological fluids and cell culture media, as well as in gas samples such as exhaled breath. The facility uses a Sievers Instruments Model 280 Nitric Oxide Analyzer, a highly sensitive (picomole range), selective detector for nitric oxide, designed specifically for medical and research applications. The measurement of NO is based on the chemiluminescent reaction of NO with O3 (both nitrite and nitrate are reduced to NO using vanadium chloride).

Please call for consultation and estimate of cost.

CONTACT
Dr. Maja Nowakowski
Department of Pathology
Basic Science Building, Room 4-109
(718) 270-2206 - Fax (718) 270-3313
Box 25
mnowakowski@downstate.edu


Radioactive Acquisition and Disposal