The State University of New York Downstate Medical Center/State University Hospital,(DMC) has adopted policies and administrative procedures to assure compliance with the Animal Welfare Act [Public Law 89-544, 1966, as amended, (PL. 91-579 and PL. 94-279), 7 U.S.C. 2131 et.seq.], the Code of Federal Regulations, (9 C.F.R. Parts 1, 2 and 3), the State of New York Department of Health Administrative Rules and Regulations (Chapter II, Subchapter D, Part 55), and the Public Health Service (National Institutes of Health) Policy on Humane Care and Use of Laboratory Animals. All research investigators and educators will be required to fully comply with DMC's policies and procedures and any additional sponsor specific requirements.